Cargando…

Mesangial Cell-Specific Antibodies Are Central to the Pathogenesis of Lupus Nephritis

Not only is nephritis a common complaint in systemic lupus erythematosus, but it is also the most life-threatening complication of the disease. Anti-double-stranded DNA antibodies (Abs), which are found in up to 80% of these patients, might be nephritogenic per se. That is, they may cross-react with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seret, Guillaume, Le Meur, Yannick, Renaudineau, Yves, Youinou, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227425/ https://www.ncbi.nlm.nih.gov/pubmed/22162716 http://dx.doi.org/10.1155/2012/579670

Ejemplares similares

Homozygous FCGR3A-158F mutation is associated with delayed B-cell depletion following rituximab but with preserved efficacy in a patient with refractory lupus nephritis
por: Seret, Guillaume, et al.
Publicado: (2013)

The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis
por: Youinou, Pierre, et al.
Publicado: (2009)

Mesangial cell: A hub in lupus nephritis
por: Liu, Mengdi, et al.
Publicado: (2022)

Lupus Nephritis Risk Factors and Biomarkers: An Update
por: Renaudineau, Yves, et al.
Publicado: (2023)

The Pathogenesis of Lupus Nephritis
por: Sterner, Rosalie M., et al.
Publicado: (2014)

Mesangial Cell-Binding Activity of Serum Immunoglobulin G in Patients with Lupus Nephritis
por: Yap, Desmond Y. H., et al.
Publicado: (2014)

Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus
por: Wright, Rachael D., et al.
Publicado: (2019)

Cyclophosphamide Attenuates Fibrosis in Lupus Nephritis by Regulating Mesangial Cell Cycle Progression
por: Ma, Yuehong, et al.
Publicado: (2021)

Gender Differences in the Pathogenesis and Outcome of Lupus and of Lupus Nephritis
por: Schwartzman-Morris, Julie, et al.
Publicado: (2012)

The new B-cell-specific exon 1B of the CD5 mRNA favors autoimmunity by preventing the membrane expression of CD5
por: Renaudineau, Y, et al.
Publicado: (2003)

Cell-free Fc-γ receptors IIIb, autoantibodies and related immune complexes trigger the production of G-CSF and GM-CSF in nonorgan-specific autoimmune diseases
por: Durand, V, et al.
Publicado: (2002)

Tacrolimus Induction Therapy for Nephrotic Syndrome Caused by Minimal Mesangial Lupus Nephritis with Lupus Podocytopathy: A Case-Based Review
por: Kurihara, Ibuki, et al.
Publicado: (2022)

Antiphospholipid Antibodies in Lupus Nephritis
por: Parodis, Ioannis, et al.
Publicado: (2016)

The Role of Hyaluronan and CD44 in the Pathogenesis of Lupus Nephritis
por: Yung, Susan, et al.
Publicado: (2012)

Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis
por: Tveita, Anders, et al.
Publicado: (2008)

Advances in Lupus Nephritis Pathogenesis: From Bench to Bedside
por: Obrișcă, Bogdan, et al.
Publicado: (2021)

A Case of Mesangial Proliferative Nephritis Caused by Slow Cryoglobulin
por: Hashimoto, Seiji, et al.
Publicado: (2023)

Two promoters for the CD5 gene: one operating in T cells and activated B cells and another restricted to resting B cells
por: Renaudineau, Y, et al.
Publicado: (2002)

CD11b Activity Modulates Pathogenesis of Lupus Nephritis
por: Khan, Samia Q., et al.
Publicado: (2018)

An Antinuclear Antibody-Negative Patient With Lupus Nephritis
por: Kim, Hyoun-Ah, et al.
Publicado: (2009)

The impact of antiphospholipid antibodies in children with lupus nephritis
por: Al-Mayouf, Sulaiman M., et al.
Publicado: (2015)

New insights into the role of renal resident cells in the pathogenesis of lupus nephritis
por: Kwok, Seung-Ki, et al.
Publicado: (2018)

CircRTN4 aggravates mesangial cell dysfunction by activating the miR-513a-5p/FN axis in lupus nephritis
por: Miao, Xinyan, et al.
Publicado: (2022)

Knockdown of DEC2 expression inhibits the proliferation of mesangial cells through suppressed glycolysis and p38 MAPK/Erk pathway in lupus nephritis
por: Qi, Huimeng, et al.
Publicado: (2023)

MicroRNAs in Lupus Nephritis–Role in Disease Pathogenesis and Clinical Applications
por: So, Benjamin Y. F., et al.
Publicado: (2021)

B Cell Abnormalities in Systemic Lupus Erythematosus and Lupus Nephritis—Role in Pathogenesis and Effect of Immunosuppressive Treatments
por: Yap, Desmond Y. H., et al.
Publicado: (2019)

Autoantibodies and Resident Renal Cells in the Pathogenesis of Lupus Nephritis : Getting to Know the Unknown
por: Yung, Susan, et al.
Publicado: (2012)

Modulation of cyclins and p53 in mesangial cell proliferation and apoptosis during Habu nephritis
por: Lu, Yang, et al.
Publicado: (2015)

Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis
por: Becker-Merok, Andrea, et al.
Publicado: (2006)

Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl-2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice
por: Wang, Baodong, et al.
Publicado: (2018)

Correction: Knockdown of DEC2 expression inhibits the proliferation of mesangial cells through suppressed glycolysis and p38 MAPK/Erk pathway in lupus nephritis
por: Qi, Huimeng, et al.
Publicado: (2023)

Mesangial cells of lupus-prone mice are sensitive to chemokine production
por: Ka, Shuk-Man, et al.
Publicado: (2007)

Anti‐retinoblastoma Protein Antibodies: A New Specificity in Systemic Lupus Erythematosus Associated With Protection Against Lupus Nephritis
por: Goules, Andreas, et al.
Publicado: (2019)

Metabolomics approach reveals urine biomarkers and pathways associated with the pathogenesis of lupus nephritis
por: Kalantari, Shiva, et al.
Publicado: (2019)

Pediatric lupus nephritis
por: Pinheiro, Sergio Veloso Brant, et al.
Publicado: (2018)

Hyperhomocysteinemia and Lupus Nephritis
por: Timlin, Homa, et al.
Publicado: (2019)

Management of Lupus Nephritis
por: Tamirou, Farah, et al.
Publicado: (2021)

Lupus Nephritis and Dysbiosis
por: Monticolo, Marta, et al.
Publicado: (2023)

Efficacy of novel monoclonal antibody belimumab in the treatment of lupus nephritis
por: Frieri, Marianne, et al.
Publicado: (2015)

Anti-Myeloperoxidase Antibodies Associate with Future Proliferative Lupus Nephritis
por: Olson, S. W., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1fn9kl7g91g5i2oejgp2qa6760