Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease

Alzheimer's disease (AD) is a progressive and fatal brain disease, but the pathogenesis of AD is still not understood. Aberrant cell-cycle re-entry of neuronal cells is emerging as a potential pathological mechanism in AD. Polo-like kinase 1 (Plk1) is an established regulator of many cell cycle...

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Detalles Bibliográficos
Autores principales: Song, Bing, Davis, Korbin, Liu, X. Shawn, Lee, Hyoung-gon, Smith, Mark, Liu, Xiaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227450/
https://www.ncbi.nlm.nih.gov/pubmed/21931181

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