Dose-Dependent Change in Elimination Kinetics of Ethanol due to Shift of Dominant Metabolizing Enzyme from ADH 1 (Class I) to ADH 3 (Class III) in Mouse

ADH 1 and ADH 3 are major two ADH isozymes in the liver, which participate in systemic alcohol metabolism, mainly distributing in parenchymal and in sinusoidal endothelial cells of the liver, respectively. We investigated how these two ADHs contribute to the elimination kinetics of blood ethanol by...

Descripción completa

Detalles Bibliográficos
Autores principales: Haseba, Takeshi, Kameyama, Kouji, Mashimo, Keiko, Ohno, Youkichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227458/
https://www.ncbi.nlm.nih.gov/pubmed/22164338
http://dx.doi.org/10.1155/2012/408190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227458/
https://www.ncbi.nlm.nih.gov/pubmed/22164338
http://dx.doi.org/10.1155/2012/408190

Ejemplares similares