Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans

Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE(−/−) mice, we induced unstable plaque with usin...

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Detalles Bibliográficos
Autores principales: Segers, Dolf, Lipton, Jonathan A., Leenen, Pieter J. M., Cheng, Caroline, Tempel, Dennie, Pasterkamp, Gerard, Moll, Frans L., de Crom, Rini, Krams, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227498/
https://www.ncbi.nlm.nih.gov/pubmed/22164344
http://dx.doi.org/10.4061/2011/936109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227498/
https://www.ncbi.nlm.nih.gov/pubmed/22164344
http://dx.doi.org/10.4061/2011/936109

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