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Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans
Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE(−/−) mice, we induced unstable plaque with usin...
Autores principales: | Segers, Dolf, Lipton, Jonathan A., Leenen, Pieter J. M., Cheng, Caroline, Tempel, Dennie, Pasterkamp, Gerard, Moll, Frans L., de Crom, Rini, Krams, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227498/ https://www.ncbi.nlm.nih.gov/pubmed/22164344 http://dx.doi.org/10.4061/2011/936109 |
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