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Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis

BACKGROUND: Mitochondria have roles or appear to have roles in the pathogenesis of several chronic age-related and acute neurological disorders, including Charcot-Marie-Tooth disease, amyotrophic lateral sclerosis, Parkinson's disease, and cerebral ischemia, and could be critical targets for de...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Pan, Yan, Price, Ann, Martin, Lee J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227596/
https://www.ncbi.nlm.nih.gov/pubmed/22047141
http://dx.doi.org/10.1186/1750-1326-6-75