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Molecular dynamics simulations and in silico peptide ligand screening of the Elk-1 ETS domain
BACKGROUND: The Elk-1 transcription factor is a member of a group of proteins called ternary complex factors, which serve as a paradigm for gene regulation in response to extracellular signals. Its deregulation has been linked to multiple human diseases including the development of tumours. The work...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227621/ https://www.ncbi.nlm.nih.gov/pubmed/22044511 http://dx.doi.org/10.1186/1758-2946-3-49 |