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Efficient Production of HIV-1 Virus-Like Particles from a Mammalian Expression Vector Requires the N-Terminal Capsid Domain

It is now well accepted that the structural protein Pr55(Gag) is sufficient by itself to produce HIV-1 virus-like particles (VLPs). This polyprotein precursor contains different domains including matrix, capsid, SP1, nucleocapsid, SP2 and p6. In the present study, we wanted to determine by mutagenes...

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Detalles Bibliográficos
Autores principales:	Jalaguier, Pascal, Turcotte, Karine, Danylo, Alexis, Cantin, Réjean, Tremblay, Michel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227654/ https://www.ncbi.nlm.nih.gov/pubmed/22140574 http://dx.doi.org/10.1371/journal.pone.0028314

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