Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors

The phosphoinositide 3-kinases (PI3Ks) constitute an important family of lipid kinase enzymes that control a range of cellular processes through their regulation of a network of signal transduction pathways, and have emerged as important therapeutic targets in the context of cancer, inflammation and...

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Detalles Bibliográficos
Autores principales: Shuttleworth, S.J, Silva, F.A, Cecil, A.R.L, Tomassi, C.D, Hill, T.J, Raynaud, F.I, Clarke, P.A, Workman, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228236/
https://www.ncbi.nlm.nih.gov/pubmed/21649578
http://dx.doi.org/10.2174/092986711796011229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228236/
https://www.ncbi.nlm.nih.gov/pubmed/21649578
http://dx.doi.org/10.2174/092986711796011229

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