Performance of a New HPV Cervi-Collect Collection and Transportation Kit

Background. Liquid-based Pap (L-Pap) media are used for Pap and human papillomavirus (HPV) testing. Objectives. To compare RealTime High Risk (HR) HPV testing of a new collection kit (Cervi-Collect) and PreservCyt L-Pap specimens. To determine ease of use and safety of Cervi-Collect. Methods. L-Pap...

Descripción completa

Detalles Bibliográficos
Autores principales: Chernesky, M., Huang, S., Jang, D., Erickson, B., Salituro, J., Engel, H., Gilchrist, J., Neuscheler, P., Mak, W. B., Abravaya, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228283/
https://www.ncbi.nlm.nih.gov/pubmed/22174716
http://dx.doi.org/10.1155/2012/503432
_version_ 1782217805254361088
author Chernesky, M.
Huang, S.
Jang, D.
Erickson, B.
Salituro, J.
Engel, H.
Gilchrist, J.
Neuscheler, P.
Mak, W. B.
Abravaya, K.
author_facet Chernesky, M.
Huang, S.
Jang, D.
Erickson, B.
Salituro, J.
Engel, H.
Gilchrist, J.
Neuscheler, P.
Mak, W. B.
Abravaya, K.
author_sort Chernesky, M.
collection PubMed
description Background. Liquid-based Pap (L-Pap) media are used for Pap and human papillomavirus (HPV) testing. Objectives. To compare RealTime High Risk (HR) HPV testing of a new collection kit (Cervi-Collect) and PreservCyt L-Pap specimens. To determine ease of use and safety of Cervi-Collect. Methods. L-Pap samples (n = 203) were tested with HC2 and RealTime HR HPV and Cervi-Collect with RealTime HR HPV. Discordant samples were genotyped. Results. L-Pap and Cervi-Collect specimens tested by RealTime HR HPV showed 93.1% agreement (Kappa 0.86). RealTime HR HPV and HC2 on L-Pap had 90.3% agreement (Kappa 0.80). RealTime HR HPV on Cervi-Collect and HC2 on L-Pap showed 88.2% agreement (Kappa 0.76). Sixteen of 21 samples which were HC2 negative and RealTime HR HPV positive on L-Pap or Cervi-Collect contained HR HPV genotypes. Eleven healthcare collectors were in strong agreement on a usability and safety questionnaire. Conclusion. Cervi-Collect samples were easy to collect and showed strong agreement with L-Pap samples tested with RealTime HR HPV or HC2.
format Online
Article
Text
id pubmed-3228283
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-32282832011-12-15 Performance of a New HPV Cervi-Collect Collection and Transportation Kit Chernesky, M. Huang, S. Jang, D. Erickson, B. Salituro, J. Engel, H. Gilchrist, J. Neuscheler, P. Mak, W. B. Abravaya, K. J Oncol Clinical Study Background. Liquid-based Pap (L-Pap) media are used for Pap and human papillomavirus (HPV) testing. Objectives. To compare RealTime High Risk (HR) HPV testing of a new collection kit (Cervi-Collect) and PreservCyt L-Pap specimens. To determine ease of use and safety of Cervi-Collect. Methods. L-Pap samples (n = 203) were tested with HC2 and RealTime HR HPV and Cervi-Collect with RealTime HR HPV. Discordant samples were genotyped. Results. L-Pap and Cervi-Collect specimens tested by RealTime HR HPV showed 93.1% agreement (Kappa 0.86). RealTime HR HPV and HC2 on L-Pap had 90.3% agreement (Kappa 0.80). RealTime HR HPV on Cervi-Collect and HC2 on L-Pap showed 88.2% agreement (Kappa 0.76). Sixteen of 21 samples which were HC2 negative and RealTime HR HPV positive on L-Pap or Cervi-Collect contained HR HPV genotypes. Eleven healthcare collectors were in strong agreement on a usability and safety questionnaire. Conclusion. Cervi-Collect samples were easy to collect and showed strong agreement with L-Pap samples tested with RealTime HR HPV or HC2. Hindawi Publishing Corporation 2012 2011-11-14 /pmc/articles/PMC3228283/ /pubmed/22174716 http://dx.doi.org/10.1155/2012/503432 Text en Copyright © 2012 M. Chernesky et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Chernesky, M.
Huang, S.
Jang, D.
Erickson, B.
Salituro, J.
Engel, H.
Gilchrist, J.
Neuscheler, P.
Mak, W. B.
Abravaya, K.
Performance of a New HPV Cervi-Collect Collection and Transportation Kit
title Performance of a New HPV Cervi-Collect Collection and Transportation Kit
title_full Performance of a New HPV Cervi-Collect Collection and Transportation Kit
title_fullStr Performance of a New HPV Cervi-Collect Collection and Transportation Kit
title_full_unstemmed Performance of a New HPV Cervi-Collect Collection and Transportation Kit
title_short Performance of a New HPV Cervi-Collect Collection and Transportation Kit
title_sort performance of a new hpv cervi-collect collection and transportation kit
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228283/
https://www.ncbi.nlm.nih.gov/pubmed/22174716
http://dx.doi.org/10.1155/2012/503432
work_keys_str_mv AT cherneskym performanceofanewhpvcervicollectcollectionandtransportationkit
AT huangs performanceofanewhpvcervicollectcollectionandtransportationkit
AT jangd performanceofanewhpvcervicollectcollectionandtransportationkit
AT ericksonb performanceofanewhpvcervicollectcollectionandtransportationkit
AT salituroj performanceofanewhpvcervicollectcollectionandtransportationkit
AT engelh performanceofanewhpvcervicollectcollectionandtransportationkit
AT gilchristj performanceofanewhpvcervicollectcollectionandtransportationkit
AT neuschelerp performanceofanewhpvcervicollectcollectionandtransportationkit
AT makwb performanceofanewhpvcervicollectcollectionandtransportationkit
AT abravayak performanceofanewhpvcervicollectcollectionandtransportationkit

Ejemplares similares