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The IQ Motif is Crucial for Ca(v)1.1 Function

Ca(2+)-dependent modulation via calmodulin, with consensus CaM-binding IQ motif playing a key role, has been documented for most high-voltage-activated Ca(2+) channels. The skeletal muscle Ca(v)1.1 also exhibits Ca(2+)-/CaM-dependent modulation. Here, whole-cell Ca(2+) current, Ca(2+) transient, and...

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Detalles Bibliográficos
Autor principal: Stroffekova, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228397/
https://www.ncbi.nlm.nih.gov/pubmed/22162637
http://dx.doi.org/10.1155/2011/504649