Cargando…
Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag
BACKGROUND: The identification and characterization of several interferon (IFN)-induced cellular HIV-1 restriction factors, defined as host cellular proteins or factors that restrict or inhibit the HIV-1 life cycle, have provided insight into the IFN response towards HIV-1 infection and identified n...
Autores principales: | Woods, Matthew W, Kelly, Jenna N, Hattlmann, Clayton J, Tong, Jessica GK, Xu, Li S, Coleman, Macon D, Quest, Graeme R, Smiley, James R, Barr, Stephen D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228677/ https://www.ncbi.nlm.nih.gov/pubmed/22093708 http://dx.doi.org/10.1186/1742-4690-8-95 |
Ejemplares similares
-
HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response
por: Mathieu, Nicholas A., et al.
Publicado: (2021) -
Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation
por: Qin, Ying, et al.
Publicado: (2023) -
TRIM22: A Diverse and Dynamic Antiviral Protein
por: Hattlmann, Clayton J., et al.
Publicado: (2012) -
Interferon-Induced HERC5 Inhibits Ebola Virus Particle Production and Is Antagonized by Ebola Glycoprotein
por: Paparisto, Ermela, et al.
Publicado: (2021) -
Evolution-Guided Structural and Functional Analyses of the HERC Family Reveal an Ancient Marine Origin and Determinants of Antiviral Activity
por: Paparisto, Ermela, et al.
Publicado: (2018)