Cargando…

Down-Regulation of DNA Mismatch Repair Enhances Initiation and Growth of Neuroblastoma and Brain Tumour Multicellular Spheroids

Multicellular tumour spheroid (MCTS) cultures are excellent model systems for simulating the development and microenvironmental conditions of in vivo tumour growth. Many documented cell lines can generate differentiated MCTS when cultured in suspension or in a non-adhesive environment. While physiol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Collins, Samuel L., Hervé, Rodolphe, Keevil, C. W., Blaydes, Jeremy P., Webb, Jeremy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228745/ https://www.ncbi.nlm.nih.gov/pubmed/22145025 http://dx.doi.org/10.1371/journal.pone.0028123

Ejemplares similares

Unsuccessful mitosis in multicellular tumour spheroids
por: Molla, Annie, et al.
Publicado: (2017)

Growth and radiosensitivity of malignant melanoma multicellular spheroids initiated directly from surgical specimens of tumours in man.
por: Rofstad, E. K.
Publicado: (1986)

Response of EMT6 multicellular tumour spheroids to hyperthermia and cytotoxic drugs.
por: Morgan, J. E., et al.
Publicado: (1981)

Heterogeneous response of individual multicellular tumour spheroids to immunotoxins and ricin toxin.
por: Chignola, R., et al.
Publicado: (1995)

A method for estimating the oxygen consumption rate in multicellular tumour spheroids
por: Grimes, David Robert, et al.
Publicado: (2014)

Multicellular tumour spheroids: a model for combined in vivo/in vitro assay of tumour immunity.
por: Culo, F., et al.
Publicado: (1980)

In vitro cytotoxic drug sensitivity testing of human tumour xenografts grown as multicellular tumour spheroids.
por: Jones, A. C., et al.
Publicado: (1982)

Optical coherence tomography complements confocal microscopy for investigation of multicellular tumour spheroids
por: Hari, Neelam, et al.
Publicado: (2019)

Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs
por: Dexheimer, Thomas S., et al.
Publicado: (2023)

Increased doxorubicin uptake and toxicity in multicellular tumour spheroids treated with DC electrical fields
por: Sauer, H, et al.
Publicado: (1999)

Resistance of Lung Cancer Cells Grown as Multicellular Tumour Spheroids to Zinc Sulfophthalocyanine Photosensitization
por: Manoto, Sello Lebohang, et al.
Publicado: (2015)

Evaluating nanoparticle localisation in glioblastoma multicellular tumour spheroids by surface enhanced Raman scattering
por: McCabe, Samantha M., et al.
Publicado: (2023)

Linking hypoxia, DNA damage and proliferation in multicellular tumor spheroids
por: Riffle, Stephen, et al.
Publicado: (2017)

Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids
por: Valeria, Ponce de León, et al.
Publicado: (2005)

The Efficacy of Zinc Phthalocyanine Nanoconjugate on Melanoma Cells Grown as Three-Dimensional Multicellular Tumour Spheroids
por: Nkune, Nkune Williams, et al.
Publicado: (2023)

Resistance to vincristine of human cells grown as multicellular spheroids.
por: Wibe, E.
Publicado: (1980)

Increased nanoparticle penetration in collagenase-treated multicellular spheroids
por: Goodman, Thomas T, et al.
Publicado: (2007)

Natural and Synthetic Biomaterials for Engineering Multicellular Tumor Spheroids
por: Kamatar, Advika, et al.
Publicado: (2020)

Challenges of applying multicellular tumor spheroids in preclinical phase
por: Han, Se Jik, et al.
Publicado: (2021)

Multicellular Tumor Spheroids in Nanomedicine Research: A Perspective
por: Rossi, Martina, et al.
Publicado: (2022)

Protocol for generation of multicellular spheroids through reduced gravity
por: Zinn, Dylan A., et al.
Publicado: (2023)

Single Spheroid Metabolomics: Optimizing Sample Preparation of Three-Dimensional Multicellular Tumor Spheroids
por: Rusz, Mate, et al.
Publicado: (2019)

Morphogenetic and neuronal characterization of human neuroblastoma multicellular spheroids cultured under undifferentiated and all-trans-retinoic acid-differentiated conditions
por: Jung, Gwon-Soo, et al.
Publicado: (2013)

The radiation response of V79 and human tumour multicellular spheroids--cell survival and growth delay studies.
por: West, C. M., et al.
Publicado: (1984)

Photocytotoxic efficacy of sulphonated species of aluminium phthalocyanine against cell monolayers, multicellular spheroids and in vivo tumours.
por: Chan, W. S., et al.
Publicado: (1991)

Multidrug resistance characterization in multicellular tumour spheroids from two human lung cancer cell lines
por: Barrera-Rodríguez, Raúl, et al.
Publicado: (2015)

An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids
por: Mao, Xinjian, et al.
Publicado: (2018)

Growth and radiation sensitivity of the MLS human ovarian carcinoma cell line grown as multicellular spheroids and xenografted tumours.
por: Rofstad, E. K., et al.
Publicado: (1989)

Multicellular Tumour Spheroid as a model for evaluation of [(18)F]FDG as biomarker for breast cancer treatment monitoring
por: Monazzam, Azita, et al.
Publicado: (2006)

Endothelial cell mitogen released from HT29 tumour cells grown in monolayer or multicellular spheroid culture.
por: Acker, H., et al.
Publicado: (1990)

Enhancement of thermal killing by polyamines V. The response of EMT6 multicellular tumour spheroids versus monolayer cells.
por: Ben-Hur, E., et al.
Publicado: (1983)

Enhancement of transforming growth factor-alpha synthesis in multicellular tumour spheroids of A431 squamous carcinoma cells.
por: Laderoute, K. R., et al.
Publicado: (1992)

Application of the multicellular tumour spheroid model to screen PET tracers for analysis of early response of chemotherapy in breast cancer
por: Monazzam, Azita, et al.
Publicado: (2007)

Influence of glucose and oxygen supply conditions on the oxygenation of multicellular spheroids.
por: Mueller-Klieser, W., et al.
Publicado: (1986)

Multicellular Self-Assembled Spheroidal Model of the Blood Brain Barrier
por: Urich, Eduard, et al.
Publicado: (2013)

Study of the Chemotactic Response of Multicellular Spheroids in a Microfluidic Device
por: Ayuso, Jose M., et al.
Publicado: (2015)

Modeling tumor cell adaptations to hypoxia in multicellular tumor spheroids
por: Riffle, Stephen, et al.
Publicado: (2017)

Radiosensitivity of quiescent and proliferating cells grown as multicellular tumor spheroids
por: Onozato, Yusuke, et al.
Publicado: (2017)

Recent Advances in Multicellular Tumor Spheroid Generation for Drug Screening
por: Lee, Kwang-Ho, et al.
Publicado: (2021)

Heterotypic Multicellular Spheroids as Experimental and Preclinical Models of Sprouting Angiogenesis
por: Vakhrushev, Igor V., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fiup1efi2q0ap9cn6nel0r13vo