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Acid Stability of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity

Highly pathogenic avian influenza viruses of the H5N1 subtype continue to threaten agriculture and human health. Here, we use biochemistry and x-ray crystallography to reveal how amino-acid variations in the hemagglutinin (HA) protein contribute to the pathogenicity of H5N1 influenza virus in chicke...

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Detalles Bibliográficos
Autores principales:	DuBois, Rebecca M., Zaraket, Hassan, Reddivari, Muralidhar, Heath, Richard J., White, Stephen W., Russell, Charles J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228800/ https://www.ncbi.nlm.nih.gov/pubmed/22144894 http://dx.doi.org/10.1371/journal.ppat.1002398

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