Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans

One major expectation from the transcriptome in humans is to characterize the biological basis of associations identified by genome-wide association studies. So far, few cis expression quantitative trait loci (eQTLs) have been reliably related to disease susceptibility. Trans-regulating mechanisms m...

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Detalles Bibliográficos
Autores principales: Rotival, Maxime, Zeller, Tanja, Wild, Philipp S., Maouche, Seraya, Szymczak, Silke, Schillert, Arne, Castagné, Raphaele, Deiseroth, Arne, Proust, Carole, Brocheton, Jessy, Godefroy, Tiphaine, Perret, Claire, Germain, Marine, Eleftheriadis, Medea, Sinning, Christoph R., Schnabel, Renate B., Lubos, Edith, Lackner, Karl J., Rossmann, Heidi, Münzel, Thomas, Rendon, Augusto, Consortium, Cardiogenics, Erdmann, Jeanette, Deloukas, Panos, Hengstenberg, Christian, Diemert, Patrick, Montalescot, Gilles, Ouwehand, Willem H., Samani, Nilesh J., Schunkert, Heribert, Tregouet, David-Alexandre, Ziegler, Andreas, Goodall, Alison H., Cambien, François, Tiret, Laurence, Blankenberg, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228821/
https://www.ncbi.nlm.nih.gov/pubmed/22144904
http://dx.doi.org/10.1371/journal.pgen.1002367

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