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Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia

BACKGROUND: Glucocorticoids such as prednisolone and dexamethasone are critical drugs used in multi-agent chemotherapy protocols used to treat acute lymphoblastic leukemia (ALL), and response to glucocorticoids is highly predictive of outcome. The NOD/SCID xenograft mouse model of ALL is a clinicall...

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Detalles Bibliográficos
Autores principales:	Bhadri, Vivek A, Cowley, Mark J, Kaplan, Warren, Trahair, Toby N, Lock, Richard B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228854/ https://www.ncbi.nlm.nih.gov/pubmed/22093874 http://dx.doi.org/10.1186/1471-2164-12-565

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