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Mutational analysis of xenobiotic metabolizing genes (CYP1A1 and GSTP1) in sporadic head and neck cancer patients
CYP1A1 is the phase I enzyme that detoxifies the carcinogen or converts it into a more electrophilic form, metabolized by phase II enzymes like GSTP1. These detoxifying genes have been extensively studied in association with head and neck cancer (HNC) in different ethnic groups worldwide. The curren...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229104/ https://www.ncbi.nlm.nih.gov/pubmed/22215953 http://dx.doi.org/10.1590/S1415-47572011005000034 |