Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury

The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L(−1) methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (gr...

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Autores principales: da Rocha, Carlos Alberto Machado, da Cunha, Lorena Araújo, da Silva Pinheiro, Raul Henrique, de Oliveira Bahia, Marcelo, Burbano, Rommel Mario Rodríguez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2011
Materias:
Mutagenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229127/
https://www.ncbi.nlm.nih.gov/pubmed/22215976
http://dx.doi.org/10.1590/S1415-47572011000400024
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author da Rocha, Carlos Alberto Machado
da Cunha, Lorena Araújo
da Silva Pinheiro, Raul Henrique
de Oliveira Bahia, Marcelo
Burbano, Rommel Mario Rodríguez
author_facet da Rocha, Carlos Alberto Machado
da Cunha, Lorena Araújo
da Silva Pinheiro, Raul Henrique
de Oliveira Bahia, Marcelo
Burbano, Rommel Mario Rodríguez
author_sort da Rocha, Carlos Alberto Machado
collection PubMed
description The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L(−1) methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure.
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spelling pubmed-32291272012-01-03 Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury da Rocha, Carlos Alberto Machado da Cunha, Lorena Araújo da Silva Pinheiro, Raul Henrique de Oliveira Bahia, Marcelo Burbano, Rommel Mario Rodríguez Genet Mol Biol Mutagenesis The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L(−1) methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure. Sociedade Brasileira de Genética 2011-10-01 2011 /pmc/articles/PMC3229127/ /pubmed/22215976 http://dx.doi.org/10.1590/S1415-47572011000400024 Text en Copyright © 2011, Sociedade Brasileira de Genética. Printed in Brazil License information: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Mutagenesis
da Rocha, Carlos Alberto Machado
da Cunha, Lorena Araújo
da Silva Pinheiro, Raul Henrique
de Oliveira Bahia, Marcelo
Burbano, Rommel Mario Rodríguez
Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_full Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_fullStr Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_full_unstemmed Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_short Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_sort studies of micronuclei and other nuclear abnormalities in red blood cells of colossoma macropomum exposed to methylmercury
topic Mutagenesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229127/
https://www.ncbi.nlm.nih.gov/pubmed/22215976
http://dx.doi.org/10.1590/S1415-47572011000400024
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