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Seven-year clinical follow-up of premanifest carriers of Huntington's disease

Detecting subtle clinical abnormalities in the ‘premanifest’ phase of Huntington’s disease (HD) is of importance in the development of instruments to monitor early therapeutic intervention trials. The current study examined changes in motor function, cognition and behaviour over a period of seven ye...

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Detalles Bibliográficos
Autores principales: Hart, Ellen, Middelkoop, Huub, Jurgens, Caroline K, Witjes-Ané, Marie-Noëlle W, Roos, Raymund A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229160/
https://www.ncbi.nlm.nih.gov/pubmed/22173894
http://dx.doi.org/10.1371/currents.RRN1288