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Seven-year clinical follow-up of premanifest carriers of Huntington's disease
Detecting subtle clinical abnormalities in the ‘premanifest’ phase of Huntington’s disease (HD) is of importance in the development of instruments to monitor early therapeutic intervention trials. The current study examined changes in motor function, cognition and behaviour over a period of seven ye...
Autores principales: | Hart, Ellen, Middelkoop, Huub, Jurgens, Caroline K, Witjes-Ané, Marie-Noëlle W, Roos, Raymund A.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229160/ https://www.ncbi.nlm.nih.gov/pubmed/22173894 http://dx.doi.org/10.1371/currents.RRN1288 |
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