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Alzheimer's - Looking beyond plaques

Mounting evidence shows that inflammation plays a critical role in causing Alzheimer’s disease. Over the last few decades we have gone from a situation where inflammation was generally believed to have no role in the disease to the current picture where chronic activation of IL-1 inflammation has be...

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Detalles Bibliográficos
Autor principal: Griffin, W. Sue T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229272/
https://www.ncbi.nlm.nih.gov/pubmed/22162727
http://dx.doi.org/10.3410/M3-24
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author Griffin, W. Sue T.
author_facet Griffin, W. Sue T.
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description Mounting evidence shows that inflammation plays a critical role in causing Alzheimer’s disease. Over the last few decades we have gone from a situation where inflammation was generally believed to have no role in the disease to the current picture where chronic activation of IL-1 inflammation has been shown to account for many of the hallmarks of the disease. This review is a personal account of the quest to prove that inflammation plays a critical role in causing Alzheimer’s disease.
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spelling pubmed-32292722011-12-08 Alzheimer's - Looking beyond plaques Griffin, W. Sue T. F1000 Med Rep Review Article Mounting evidence shows that inflammation plays a critical role in causing Alzheimer’s disease. Over the last few decades we have gone from a situation where inflammation was generally believed to have no role in the disease to the current picture where chronic activation of IL-1 inflammation has been shown to account for many of the hallmarks of the disease. This review is a personal account of the quest to prove that inflammation plays a critical role in causing Alzheimer’s disease. Faculty of 1000 Ltd 2011-12-01 /pmc/articles/PMC3229272/ /pubmed/22162727 http://dx.doi.org/10.3410/M3-24 Text en © 2011 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Griffin, W. Sue T.
Alzheimer's - Looking beyond plaques
title Alzheimer's - Looking beyond plaques
title_full Alzheimer's - Looking beyond plaques
title_fullStr Alzheimer's - Looking beyond plaques
title_full_unstemmed Alzheimer's - Looking beyond plaques
title_short Alzheimer's - Looking beyond plaques
title_sort alzheimer's - looking beyond plaques
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229272/
https://www.ncbi.nlm.nih.gov/pubmed/22162727
http://dx.doi.org/10.3410/M3-24
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