Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints

BACKGROUND: The HIV-1 genome is subject to pressures that target the virus resulting in escape and adaptation. On the other hand, there is a requirement for sequence conservation because of functional and structural constraints. Mapping the sites of selective pressure and conservation on the viral g...

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Detalles Bibliográficos
Autores principales: Snoeck, Joke, Fellay, Jacques, Bartha, István, Douek, Daniel C, Telenti, Amalio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229471/
https://www.ncbi.nlm.nih.gov/pubmed/22044801
http://dx.doi.org/10.1186/1742-4690-8-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229471/
https://www.ncbi.nlm.nih.gov/pubmed/22044801
http://dx.doi.org/10.1186/1742-4690-8-87

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