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Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints
BACKGROUND: The HIV-1 genome is subject to pressures that target the virus resulting in escape and adaptation. On the other hand, there is a requirement for sequence conservation because of functional and structural constraints. Mapping the sites of selective pressure and conservation on the viral g...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229471/ https://www.ncbi.nlm.nih.gov/pubmed/22044801 http://dx.doi.org/10.1186/1742-4690-8-87 |