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Nicotinamide Inhibits Alkylating Agent-Induced Apoptotic Neurodegeneration in the Developing Rat Brain

BACKGROUND: Exposure to the chemotherapeutic alkylating agent thiotepa during brain development leads to neurological complications arising from neurodegeneration and irreversible damage to the developing central nerve system (CNS). Administration of single dose of thiotepa in 7-d postnatal (P7) rat...

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Detalles Bibliográficos
Autores principales:	Ullah, Najeeb, Lee, Hae Young, Naseer, Muhammad Imran, Ullah, Ikram, Suh, Joo Won, Kim, Myeong Ok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229474/ https://www.ncbi.nlm.nih.gov/pubmed/22164206 http://dx.doi.org/10.1371/journal.pone.0027093

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