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Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells

BACKGROUND: Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4. These experiments should contribute to the kn...

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Detalles Bibliográficos
Autores principales:	Bártová, Eva, Šustáčková, Gabriela, Stixová, Lenka, Kozubek, Stanislav, Legartová, Soňa, Foltánková, Veronika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229488/ https://www.ncbi.nlm.nih.gov/pubmed/22164208 http://dx.doi.org/10.1371/journal.pone.0027281

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