Filaggrin Genotype Determines Functional and Molecular Alterations in Skin of Patients with Atopic Dermatitis and Ichthyosis Vulgaris

BACKGROUND: Several common genetic and environmental disease mechanisms are important for the pathophysiology behind atopic dermatitis (AD). Filaggrin (FLG) loss-of-function is of great significance for barrier impairment in AD and ichthyosis vulgaris (IV), which is commonly associated with AD. The...

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Detalles Bibliográficos
Autores principales: Winge, Mårten C. G., Hoppe, Torborg, Berne, Berit, Vahlquist, Anders, Nordenskjöld, Magnus, Bradley, Maria, Törmä, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229525/
https://www.ncbi.nlm.nih.gov/pubmed/22164253
http://dx.doi.org/10.1371/journal.pone.0028254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229525/
https://www.ncbi.nlm.nih.gov/pubmed/22164253
http://dx.doi.org/10.1371/journal.pone.0028254

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