Cargando…

Filaggrin Genotype Determines Functional and Molecular Alterations in Skin of Patients with Atopic Dermatitis and Ichthyosis Vulgaris

BACKGROUND: Several common genetic and environmental disease mechanisms are important for the pathophysiology behind atopic dermatitis (AD). Filaggrin (FLG) loss-of-function is of great significance for barrier impairment in AD and ichthyosis vulgaris (IV), which is commonly associated with AD. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Winge, Mårten C. G., Hoppe, Torborg, Berne, Berit, Vahlquist, Anders, Nordenskjöld, Magnus, Bradley, Maria, Törmä, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229525/ https://www.ncbi.nlm.nih.gov/pubmed/22164253 http://dx.doi.org/10.1371/journal.pone.0028254

Ejemplares similares

Genotype Study of Filaggrin Gene Loss-of-Function Mutations in Central India Population with Atopic Dermatitis and Ichthyosis Vulgaris
por: Chawla, Harsimran S., et al.
Publicado: (2023)

Filaggrin failure – from ichthyosis vulgaris to atopic eczema and beyond
por: McLean, W.H.I.
Publicado: (2016)

Ichthyosis: A Road Model for Skin Research()
por: VAHLQUIST, Anders, et al.
Publicado: (2020)

Maternal Filaggrin Mutations Increase the Risk of Atopic Dermatitis in Children: An Effect Independent of Mutation Inheritance
por: Esparza-Gordillo, Jorge, et al.
Publicado: (2015)

Filaggrin gene variants among Saudi patients with ichthyosis vulgaris
por: Alakloby, Omar Mohammed, et al.
Publicado: (2023)

Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity
por: Kezic, S, et al.
Publicado: (2011)

Skin barrier in atopic dermatitis: beyond filaggrin
por: Zaniboni, Mariana Colombini, et al.
Publicado: (2016)

Revisiting the Roles of Filaggrin in Atopic Dermatitis
por: Moosbrugger-Martinz, Verena, et al.
Publicado: (2022)

Filaggrin Mutation in Korean Patients with Atopic Dermatitis
por: On, Hye Rang, et al.
Publicado: (2017)

Patients with congenital ichthyosis and TGM1 mutations overexpress other ARCI genes in the skin: Part of a barrier repair response?
por: Zhang, Hanqian, et al.
Publicado: (2018)

3D-Organotypic Cultures to Unravel Molecular and Cellular Abnormalities in Atopic Dermatitis and Ichthyosis Vulgaris
por: Leman, Géraldine, et al.
Publicado: (2019)

Raman profiles of the stratum corneum define 3 filaggrin genotype–determined atopic dermatitis endophenotypes
por: O'Regan, Gráinne M., et al.
Publicado: (2010)

Mutations in the Filaggrin are Predisposing Factor in Korean Children With Atopic Dermatitis
por: Yu, Ho-Sung, et al.
Publicado: (2013)

The frequency of polymorphic variants of filaggrin gene and clinical atopic dermatitis
por: Filipowska-Grońska, Agata, et al.
Publicado: (2016)

Twin Studies of Atopic Dermatitis: Interpretations and Applications in the Filaggrin Era
por: Elmose, Camilla, et al.
Publicado: (2015)

Feeding filaggrin: effects of l-histidine supplementation in atopic dermatitis
por: Tan, Siao Pei, et al.
Publicado: (2017)

An Analysis of the Filaggrin Gene Polymorphism in Korean Atopic Dermatitis Patients
por: Park, Kui Young, et al.
Publicado: (2016)

Analysis of filaggrin 2 gene polymorphisms in patients with atopic dermatitis()()
por: Hertz, Amanda, et al.
Publicado: (2020)

Exome sequencing of Filaggrin and related genes in African-American children with atopic dermatitis
por: Margolis, David J., et al.
Publicado: (2014)

Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis
por: Belyaeva, Tatyana, et al.
Publicado: (2020)

The Skin and Nose Microbiome and Its Association with Filaggrin Gene Mutations in Pediatric Atopic Dermatitis
por: van Mierlo, Minke M.F., et al.
Publicado: (2022)

Association between P478S polymorphism of the filaggrin gene & atopic dermatitis
por: Kim, Seon-Young, et al.
Publicado: (2013)

Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis
por: Riethmuller, Christoph, et al.
Publicado: (2015)

Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep
por: Eaaswarkhanth, Muthukrishnan, et al.
Publicado: (2016)

Filaggrin null mutations are associated with altered circulating Tregs in atopic dermatitis
por: Moosbrugger‐Martinz, Verena, et al.
Publicado: (2018)

Filaggrin and atopic march
por: Čepelak, Ivana, et al.
Publicado: (2019)

Genetic Variation in the Epidermal Transglutaminase Genes Is Not Associated with Atopic Dermatitis
por: Liedén, Agne, et al.
Publicado: (2012)

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis
por: Cole, Christian, et al.
Publicado: (2014)

42 Polyprenol Could Prevent Loss of Filaggrin in Epithelial Cells in Atopic Dermatitis
por: Kuznecovs, Ivans S., et al.
Publicado: (2012)

The prevalence of mutations in the gene encoding filaggrin in the population of Polish patients with atopic dermatitis
por: Woźniak, Magdalena, et al.
Publicado: (2016)

Correlation of age-of-onset of Atopic Dermatitis with Filaggrin loss-of-function variant status
por: Smieszek, S. P., et al.
Publicado: (2020)

Dysbiotic Lesional Microbiome With Filaggrin Missense Variants Associate With Atopic Dermatitis in India
por: Nath, Shankha, et al.
Publicado: (2020)

Successful Treatment of an Adult with Atopic Dermatitis and Lamellar Ichthyosis Using Dupilumab
por: Binkhonain, Faisal K, et al.
Publicado: (2022)

Revertant mosaicism repairs skin lesions in a patient with keratitis-ichthyosis-deafness syndrome by second-site mutations in connexin 26
por: Gudmundsson, Sanna, et al.
Publicado: (2017)

South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin()
por: Thawer-Esmail, Fatemah, et al.
Publicado: (2014)

Rare occurrence of common filaggrin mutations in Turkish children with food allergy and atopic dermatitis
por: VARDAR ACAR, Neşe, et al.
Publicado: (2020)

Recalcitrant erythrodermic ichthyosis with atopic dermatitis successfully treated with Dupilumab in combination with Guselkumab
por: Steinhoff, M., et al.
Publicado: (2021)

Ichthyosis vulgaris: An updated review
por: Jaffar, Huda, et al.
Publicado: (2022)

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis
por: Tsuji, Gaku, et al.
Publicado: (2017)

Filaggrin Loss-of-Function Mutations Are Risk Factors for Severe Food Allergy in Children with Atopic Dermatitis
por: Astolfi, Annalisa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lt7dj15426jbiil8a43p39ofrv