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Caffeine Acts via A1 Adenosine Receptors to Disrupt Embryonic Cardiac Function

BACKGROUND: Evidence suggests that adenosine acts via cardiac A1 adenosine receptors (A1ARs) to protect embryos against hypoxia. During embryogenesis, A1ARs are the dominant regulator of heart rate, and A1AR activation reduces heart rate. Adenosine action is inhibited by caffeine, which is widely co...

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Detalles Bibliográficos
Autores principales:	Buscariollo, Daniela L., Breuer, Gregory A., Wendler, Christopher C., Rivkees, Scott A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229565/ https://www.ncbi.nlm.nih.gov/pubmed/22164264 http://dx.doi.org/10.1371/journal.pone.0028296

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