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Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion
In primary human melanoma, the membrane-type matrix metalloproteinase, MT3-MMP, is overexpressed in the most aggressive nodular-type tumors. Unlike MT1-MMP and MT2-MMP, which promote cell invasion through basement membranes and collagen type I-rich tissues, the function of MT3-MMP in tumor progressi...
Autores principales: | Tatti, Olga, Arjama, Mariliina, Ranki, Annamari, Weiss, Stephen J., Keski-Oja, Jorma, Lehti, Kaisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229567/ https://www.ncbi.nlm.nih.gov/pubmed/22164270 http://dx.doi.org/10.1371/journal.pone.0028325 |
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