Potent Neutralization of Influenza A Virus by a Single-Domain Antibody Blocking M2 Ion Channel Protein

Influenza A virus poses serious health threat to humans. Neutralizing antibodies against the highly conserved M2 ion channel is thought to offer broad protection against influenza A viruses. Here, we screened synthetic Camel single-domain antibody (VHH) libraries against native M2 ion channel protei...

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Detalles Bibliográficos
Autores principales: Wei, Guowei, Meng, Weixu, Guo, Haijiang, Pan, Weiqi, Liu, Jinsong, Peng, Tao, Chen, Ling, Chen, Chang-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229572/
https://www.ncbi.nlm.nih.gov/pubmed/22164266
http://dx.doi.org/10.1371/journal.pone.0028309

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