Cargando…

Persistent Expression of Hepatitis C Virus Non-Structural Proteins Leads to Increased Autophagy and Mitochondrial Injury in Human Hepatoma Cells

HCV infection is a major cause of chronic liver disease and liver cancer in the United States. To address the pathogenesis caused by HCV infection, recent studies have focused on the direct cytopathic effects of individual HCV proteins, with the objective of identifying their specific roles in the o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chu, Victor C., Bhattacharya, Sayanti, Nomoto, Ann, Lin, Jiahui, Zaidi, Syed Kashif, Oberley, Terry D., Weinman, Steven A., Azhar, Salman, Huang, Ting-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229600/ https://www.ncbi.nlm.nih.gov/pubmed/22164304 http://dx.doi.org/10.1371/journal.pone.0028551

Ejemplares similares

DHX15 Inhibits Autophagy and the Proliferation of Hepatoma Cells
por: Zhao, Miaomiao, et al.
Publicado: (2021)

SMC4 enhances the chemoresistance of hepatoma cells by promoting autophagy
por: Zhang, Shi-Ran, et al.
Publicado: (2022)

Eburicoic Acid, an Active Triterpenoid from the Fruiting Bodies of Basswood Cultivated Antrodia cinnamomea, Induces ER Stress-Mediated Autophagy in Human Hepatoma Cells
por: Su, Yu-Cheng, et al.
Publicado: (2012)

Iron Oxide Nanoparticles as Autophagy Intervention Agents Suppress Hepatoma Growth by Enhancing Tumoricidal Autophagy
por: Xie, Yuexia, et al.
Publicado: (2020)

Consequences of over-expression of rat Scavenger Receptor, SR-BI, in an adrenal cell model
por: Reaven, Eve, et al.
Publicado: (2006)

Saikosaponin-d Increases the Radiosensitivity of Hepatoma Cells by Adjusting Cell Autophagy
por: Tian, Yin-Di, et al.
Publicado: (2019)

Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells
por: Zhou, Weipeng, et al.
Publicado: (2020)

Uncoupling Protein 2 Regulates Palmitic Acid-Induced Hepatoma Cell Autophagy
por: Lou, Jiaxin, et al.
Publicado: (2014)

Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans
por: Bess, Amanda S., et al.
Publicado: (2012)

Suppression of autophagy by mycophenolic acid contributes to inhibition of HCV replication in human hepatoma cells
por: Fang, Shoucai, et al.
Publicado: (2017)

Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation
por: Sedlmaier, Angela, et al.
Publicado: (2011)

An Occult Hepatitis B-Derived Hepatoma Cell Line Carrying Persistent Nuclear Viral DNA and Permissive for Exogenous Hepatitis B Virus Infection
por: Lin, Chih-Lang, et al.
Publicado: (2013)

Loss of functional peroxisomes leads to increased mitochondrial biogenesis and reduced autophagy that preserve mitochondrial function
por: Chi, Lijun, et al.
Publicado: (2023)

CD133/Prominin-1-Mediated Autophagy and Glucose Uptake Beneficial for Hepatoma Cell Survival
por: Chen, Haiyang, et al.
Publicado: (2013)

Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells
por: Desjarlais, Michel, et al.
Publicado: (2014)

Alcohol-induced autophagy via upregulation of PIASy promotes HCV replication in human hepatoma cells
por: Ran, Meihua, et al.
Publicado: (2018)

Pokemon Silencing Leads to Bim-Mediated Anoikis of Human Hepatoma Cell QGY7703
por: Liu, Kun, et al.
Publicado: (2012)

Acoustic stability of a self-gravitating cylinder leading to astrostructure formation
por: Dasgupta, Sayanti, et al.
Publicado: (2023)

Tropical Cirrhosis and Hepatoma
por: Coady, Anthony
Publicado: (1976)

The anticancer flavonoid chrysin induces the unfolded protein response in hepatoma cells
por: Sun, Xiangming, et al.
Publicado: (2011)

Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway
por: Liou, An-Ting, et al.
Publicado: (2017)

Elemene Injection Induced Autophagy Protects Human Hepatoma Cancer Cells from Starvation and Undergoing Apoptosis
por: Lin, Yan, et al.
Publicado: (2014)

Mitoptosis, a Novel Mitochondrial Death Mechanism Leading Predominantly to Activation of Autophagy
por: Jangamreddy, Jaganmohan Reddy, et al.
Publicado: (2012)

Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage.
por: Li, Ning, et al.
Publicado: (2003)

Antimicrobial Utilization among Neonates and Children: A Multicenter Point Prevalence Study from Leading Children’s Hospitals in Punjab, Pakistan
por: Mustafa, Zia Ul, et al.
Publicado: (2022)

Child–Pugh Score and ABCG2-rs2231142 Genotype Independently Predict Survival in Advanced Hepatoma Patients Treated with Sorafenib
por: Huang, Po-Han, et al.
Publicado: (2022)

U12, a UDCA Derivative, Acts as an Anti-Hepatoma Drug Lead and Inhibits the mTOR/S6K1 and Cyclin/CDK Complex Pathways
por: Xu, Yang, et al.
Publicado: (2014)

Shikonin causes apoptosis by disrupting intracellular calcium homeostasis and mitochondrial function in human hepatoma cells
por: Wang, Hui, et al.
Publicado: (2018)

Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin
por: Chang, Wen-Tsan, et al.
Publicado: (2014)

Autophagy Inhibition Contributes to the Synergistic Interaction between EGCG and Doxorubicin to Kill the Hepatoma Hep3B Cells
por: Chen, Li, et al.
Publicado: (2014)

Effects of Sinapic Acid Combined with Cisplatin on the Apoptosis and Autophagy of the Hepatoma Cells HepG2 and SMMC-7721
por: Zhao, Jian, et al.
Publicado: (2021)

The Surgical Treatment of the Solitary Hepatoma
Publicado: (1931)

Antagonistic effects of selenium on lead-induced autophagy by influencing mitochondrial dynamics in the spleen of chickens
por: Han, Yujing, et al.
Publicado: (2017)

Distinct Redox Profiles of Selected Human Prostate Carcinoma Cell Lines: Implications for Rational Design of Redox Therapy
por: Chaiswing, Luksana, et al.
Publicado: (2011)

Effects of knockdown of miR-210 in combination with ionizing radiation on human hepatoma xenograft in nude mice
por: Yang, Wei, et al.
Publicado: (2013)

EVIDENCE FOR DISCONTINUOUS REPLICATION OF CIRCULAR MITOCHONDRIAL DNA MOLECULES FROM NOVIKOFF RAT ASCITES HEPATOMA CELLS
por: Koike, Katsuro, et al.
Publicado: (1974)

Streptozotocin-Induced Cytotoxicity, Oxidative Stress and Mitochondrial Dysfunction in Human Hepatoma HepG2 Cells
por: Raza, Haider, et al.
Publicado: (2012)

Targeting Autophagy Augments Berberine-Mediated Cell Death in Human Hepatoma Cells Harboring Hepatitis C Virus RNA
por: Tai, Chen-Jei, et al.
Publicado: (2020)

Saikosaponin-d increases radiation-induced apoptosis of hepatoma cells by promoting autophagy via inhibiting mTOR phosphorylation
por: Wang, Baofeng, et al.
Publicado: (2021)

ATP8B1 Deficiency Results in Elevated Mitochondrial Phosphatidylethanolamine Levels and Increased Mitochondrial Oxidative Phosphorylation in Human Hepatoma Cells
por: Gómez-Mellado, Valentina E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a5mqtogfa0nuk60f2j3bobj5f2