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UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling
Toll-like receptors (TLRs) 3, 7, 8, and 9 are localized to intracellular compartments where they encounter foreign or self nucleic acids and activate innate and adaptive immune responses. The endoplasmic reticulum (ER)-resident membrane protein, UNC93B1, is essential for intracellular trafficking an...
Autores principales: | Itoh, Hiroki, Tatematsu, Megumi, Watanabe, Ayako, Iwano, Katsunori, Funami, Kenji, Seya, Tsukasa, Matsumoto, Misako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229609/ https://www.ncbi.nlm.nih.gov/pubmed/22164301 http://dx.doi.org/10.1371/journal.pone.0028500 |
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