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Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations
BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder that can be triggered through genetic or sporadic mechanisms. MicroRNAs (miRNAs) have become a major therapeutic focus as their pervasive expression and powerful regulatory roles in disease pathogenesis...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229715/ https://www.ncbi.nlm.nih.gov/pubmed/22032330 http://dx.doi.org/10.1186/1471-2164-12-527 |