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Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma

Primary localized cutaneous nodular amyloidosis (nodular amyloidosis) is a rare and distinct type of amyloidosis, in which amyloid L deposition is limited to the skin and typically manifested as a tumefactive nodule on the acral sites. However, the definite cause of nodular amyloidosis is still unkn...

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Autores principales: Lee, Dong Yoon, Kim, Young Jin, Lee, Ji Yeoun, Kim, Mi Kyeong, Yoon, Tae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229950/
https://www.ncbi.nlm.nih.gov/pubmed/22148024
http://dx.doi.org/10.5021/ad.2011.23.4.515
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author Lee, Dong Yoon
Kim, Young Jin
Lee, Ji Yeoun
Kim, Mi Kyeong
Yoon, Tae Young
author_facet Lee, Dong Yoon
Kim, Young Jin
Lee, Ji Yeoun
Kim, Mi Kyeong
Yoon, Tae Young
author_sort Lee, Dong Yoon
collection PubMed
description Primary localized cutaneous nodular amyloidosis (nodular amyloidosis) is a rare and distinct type of amyloidosis, in which amyloid L deposition is limited to the skin and typically manifested as a tumefactive nodule on the acral sites. However, the definite cause of nodular amyloidosis is still unknown. Although it is relatively well known that the amyloid deposits in nodular amyloidosis originate from immunoglobulin light chains secreted by local plasma cells, traumatic injury to the skin has rarely been recognized as a triggering factor of nodular amyloidosis. Herein, we present a case of a 50-year-old male patient with primary localized cutaneous nodular amyloidosis, which occurred after local trauma, and discuss the relationship between traumatic damage and dermal amyloid L deposition.
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spelling pubmed-32299502011-12-06 Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma Lee, Dong Yoon Kim, Young Jin Lee, Ji Yeoun Kim, Mi Kyeong Yoon, Tae Young Ann Dermatol Case Report Primary localized cutaneous nodular amyloidosis (nodular amyloidosis) is a rare and distinct type of amyloidosis, in which amyloid L deposition is limited to the skin and typically manifested as a tumefactive nodule on the acral sites. However, the definite cause of nodular amyloidosis is still unknown. Although it is relatively well known that the amyloid deposits in nodular amyloidosis originate from immunoglobulin light chains secreted by local plasma cells, traumatic injury to the skin has rarely been recognized as a triggering factor of nodular amyloidosis. Herein, we present a case of a 50-year-old male patient with primary localized cutaneous nodular amyloidosis, which occurred after local trauma, and discuss the relationship between traumatic damage and dermal amyloid L deposition. Korean Dermatological Association; The Korean Society for Investigative Dermatology 2011-11 2011-11-03 /pmc/articles/PMC3229950/ /pubmed/22148024 http://dx.doi.org/10.5021/ad.2011.23.4.515 Text en Copyright © 2011 Korean Dermatological Association; The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Dong Yoon
Kim, Young Jin
Lee, Ji Yeoun
Kim, Mi Kyeong
Yoon, Tae Young
Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma
title Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma
title_full Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma
title_fullStr Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma
title_full_unstemmed Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma
title_short Primary Localized Cutaneous Nodular Amyloidosis Following Local Trauma
title_sort primary localized cutaneous nodular amyloidosis following local trauma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229950/
https://www.ncbi.nlm.nih.gov/pubmed/22148024
http://dx.doi.org/10.5021/ad.2011.23.4.515
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