Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report

A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil®, Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tis...

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Detalles Bibliográficos
Autores principales: Ha, You Jin, Han, You Jin, Choi, You Won, Myung, Ki Bum, Choi, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229957/
https://www.ncbi.nlm.nih.gov/pubmed/22148031
http://dx.doi.org/10.5021/ad.2011.23.4.544
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author Ha, You Jin
Han, You Jin
Choi, You Won
Myung, Ki Bum
Choi, Hae Young
author_facet Ha, You Jin
Han, You Jin
Choi, You Won
Myung, Ki Bum
Choi, Hae Young
author_sort Ha, You Jin
collection PubMed
description A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil®, Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tissue. These lesions showed improvement after discontinuation of sibutramine. However, 3 months later the skin lesions recurred on other sites on the lower extremities when the patient was rechallenged with the same drug for 2 weeks. Herein, we report the first case of necrotizing vasculitis induced by sibutramine.
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spelling pubmed-32299572011-12-06 Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report Ha, You Jin Han, You Jin Choi, You Won Myung, Ki Bum Choi, Hae Young Ann Dermatol Case Report A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil®, Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tissue. These lesions showed improvement after discontinuation of sibutramine. However, 3 months later the skin lesions recurred on other sites on the lower extremities when the patient was rechallenged with the same drug for 2 weeks. Herein, we report the first case of necrotizing vasculitis induced by sibutramine. Korean Dermatological Association; The Korean Society for Investigative Dermatology 2011-11 2011-11-03 /pmc/articles/PMC3229957/ /pubmed/22148031 http://dx.doi.org/10.5021/ad.2011.23.4.544 Text en Copyright © 2011 Korean Dermatological Association; The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ha, You Jin
Han, You Jin
Choi, You Won
Myung, Ki Bum
Choi, Hae Young
Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
title Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
title_full Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
title_fullStr Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
title_full_unstemmed Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
title_short Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
title_sort sibutramine (reductil®)-induced cutaneous leukocytoclastic vasculitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229957/
https://www.ncbi.nlm.nih.gov/pubmed/22148031
http://dx.doi.org/10.5021/ad.2011.23.4.544
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