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Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral
In the present study a rat animal model of lathyrism was employed to decipher whether anatomically confined alterations in collagen cross-links are sufficient to influence the mechanical properties of whole bone. Animal experiments were performed under an ethics committee approved protocol. Sixty-fo...
Autores principales: | Paschalis, E.P., Tatakis, D.N., Robins, S., Fratzl, P., Manjubala, I., Zoehrer, R., Gamsjaeger, S., Buchinger, B., Roschger, A., Phipps, R., Boskey, A.L., Dall'Ara, E., Varga, P., Zysset, P., Klaushofer, K., Roschger, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229977/ https://www.ncbi.nlm.nih.gov/pubmed/21920485 http://dx.doi.org/10.1016/j.bone.2011.08.027 |
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