XRCC1 Coordinates Disparate Responses and Multiprotein Repair Complexes Depending on the Nature and Context of the DNA Damage

XRCC1 is a scaffold protein capable of interacting with several DNA repair proteins. Here we provide evidence for the presence of XRCC1 in different complexes of sizes from 200 to 1500 kDa, and we show that immunoprecipitates using XRCC1 as bait are capable of complete repair of AP sites via both sh...

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Detalles Bibliográficos
Autores principales: Hanssen-Bauer, Audun, Solvang-Garten, Karin, Sundheim, Ottar, Peña-Diaz, Javier, Andersen, Sonja, Slupphaug, Geir, Krokan, Hans E, Wilson, David M, Akbari, Mansour, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229989/
https://www.ncbi.nlm.nih.gov/pubmed/21786338
http://dx.doi.org/10.1002/em.20663

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