Cushing's syndrome: Stepwise approach to diagnosis

The projected prevalence of Cushing's syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2–2% and it may no longer be considered as an orphan disease (2–3 cases/million/year). The recognition of CS by physicians is important for early diagnosis and treatment. Lat...

Descripción completa

Detalles Bibliográficos
Autores principales: Lila, Anurag R., Sarathi, Vijaya, Jagtap, Varsha S., Bandgar, Tushar, Menon, Padmavathy, Shah, Nalini S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230095/
https://www.ncbi.nlm.nih.gov/pubmed/22145134
http://dx.doi.org/10.4103/2230-8210.86974
_version_ 1782218031929229312
author Lila, Anurag R.
Sarathi, Vijaya
Jagtap, Varsha S.
Bandgar, Tushar
Menon, Padmavathy
Shah, Nalini S.
author_facet Lila, Anurag R.
Sarathi, Vijaya
Jagtap, Varsha S.
Bandgar, Tushar
Menon, Padmavathy
Shah, Nalini S.
author_sort Lila, Anurag R.
collection PubMed
description The projected prevalence of Cushing's syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2–2% and it may no longer be considered as an orphan disease (2–3 cases/million/year). The recognition of CS by physicians is important for early diagnosis and treatment. Late-night salivary cortisol, dexamethasone suppressiontesti, or 24-h urine free cortisol are good screening tests. Positively screened cases need stepwise evaluation by an endocrinologist. This paper discusses the importance of screening for CS and suggests a stepwise diagnostic approach to a case of suspected hypercortisolism.
format Online
Article
Text
id pubmed-3230095
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-32300952011-12-05 Cushing's syndrome: Stepwise approach to diagnosis Lila, Anurag R. Sarathi, Vijaya Jagtap, Varsha S. Bandgar, Tushar Menon, Padmavathy Shah, Nalini S. Indian J Endocrinol Metab Review Article The projected prevalence of Cushing's syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2–2% and it may no longer be considered as an orphan disease (2–3 cases/million/year). The recognition of CS by physicians is important for early diagnosis and treatment. Late-night salivary cortisol, dexamethasone suppressiontesti, or 24-h urine free cortisol are good screening tests. Positively screened cases need stepwise evaluation by an endocrinologist. This paper discusses the importance of screening for CS and suggests a stepwise diagnostic approach to a case of suspected hypercortisolism. Medknow Publications & Media Pvt Ltd 2011-10 /pmc/articles/PMC3230095/ /pubmed/22145134 http://dx.doi.org/10.4103/2230-8210.86974 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lila, Anurag R.
Sarathi, Vijaya
Jagtap, Varsha S.
Bandgar, Tushar
Menon, Padmavathy
Shah, Nalini S.
Cushing's syndrome: Stepwise approach to diagnosis
title Cushing's syndrome: Stepwise approach to diagnosis
title_full Cushing's syndrome: Stepwise approach to diagnosis
title_fullStr Cushing's syndrome: Stepwise approach to diagnosis
title_full_unstemmed Cushing's syndrome: Stepwise approach to diagnosis
title_short Cushing's syndrome: Stepwise approach to diagnosis
title_sort cushing's syndrome: stepwise approach to diagnosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230095/
https://www.ncbi.nlm.nih.gov/pubmed/22145134
http://dx.doi.org/10.4103/2230-8210.86974
work_keys_str_mv AT lilaanuragr cushingssyndromestepwiseapproachtodiagnosis
AT sarathivijaya cushingssyndromestepwiseapproachtodiagnosis
AT jagtapvarshas cushingssyndromestepwiseapproachtodiagnosis
AT bandgartushar cushingssyndromestepwiseapproachtodiagnosis
AT menonpadmavathy cushingssyndromestepwiseapproachtodiagnosis
AT shahnalinis cushingssyndromestepwiseapproachtodiagnosis

Ejemplares similares