Oxaliplatin but Not Irinotecan Impairs Posthepatectomy Liver Regeneration in a Murine Model

Introduction. We examined the murine hepatectomy model of liver regeneration (LR) in the setting of neoadjuvant chemotherapy. Methods. C57BL/6 mice were randomized to receive neoadjuvant intraperitoneal (IP) injections of a control, oxaliplatin (15 mg/kg), or irinotecan (100 mg/Kg or 250 mg/Kg) solu...

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Detalles Bibliográficos
Autores principales: Soriano, Perry A., Liu, Nian, Castillo, Erick, Foster, Brock, Artinyan, Avo, Kim, Joseph, Huang, Wendong, Wagman, Lawrence D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230113/
https://www.ncbi.nlm.nih.gov/pubmed/22164336
http://dx.doi.org/10.4061/2011/490463

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