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Strategy for intention to treat analysis in randomised trials with missing outcome data

Loss to follow-up is often hard to avoid in randomised trials. This article suggests a framework for intention to treat analysis that depends on making plausible assumptions about the missing data and including all participants in sensitivity analyses

Detalles Bibliográficos
Autores principales: White, Ian R, Horton, Nicholas J, Carpenter, James, statistics, reader in medical and social, Pocock, Stuart J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230114/
https://www.ncbi.nlm.nih.gov/pubmed/21300711
http://dx.doi.org/10.1136/bmj.d40
Descripción
Sumario:Loss to follow-up is often hard to avoid in randomised trials. This article suggests a framework for intention to treat analysis that depends on making plausible assumptions about the missing data and including all participants in sensitivity analyses