Cargando…

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

Studies using the Saccharomyces cerevisiae aging model have uncovered life span regulatory pathways that are partially conserved in higher eukaryotes(1-2). The simplicity and power of the yeast aging model can also be explored to study DNA damage and genome maintenance as well as their contributions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Min, Madia, Federica, Longo, Valter D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2011
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230202/ https://www.ncbi.nlm.nih.gov/pubmed/21989366 http://dx.doi.org/10.3791/3030

Ejemplares similares

An Optimized Competitive-Aging Method Reveals Gene-Drug Interactions Underlying the Chronological Lifespan of Saccharomyces cerevisiae
por: Avelar-Rivas, J. Abraham, et al.
Publicado: (2020)

Yeast Chronological Lifespan: Longevity Regulatory Genes and Mechanisms
por: Mirisola, Mario G., et al.
Publicado: (2022)

Dietary Restriction Depends on Nutrient Composition to Extend Chronological Lifespan in Budding Yeast Saccharomyces cerevisiae
por: Wu, Ziyun, et al.
Publicado: (2013)

Bursts of Genomic Instability Potentiate Phenotypic and Genomic Diversification in Saccharomyces cerevisiae
por: Heasley, Lydia R., et al.
Publicado: (2022)

Altered Expression of Mitochondrial NAD(+) Carriers Influences Yeast Chronological Lifespan by Modulating Cytosolic and Mitochondrial Metabolism
por: Orlandi, Ivan, et al.
Publicado: (2018)

Oxygen availability strongly affects chronological lifespan and thermotolerance in batch cultures of Saccharomyces cerevisiae
por: Bisschops, Markus M., et al.
Publicado: (2015)

Hydrogen sulfide treatment at the late growth stage of Saccharomyces cerevisiae extends chronological lifespan
por: Shah, Arman Ali, et al.
Publicado: (2021)

Availability of Amino Acids Extends Chronological Lifespan by Suppressing Hyper-Acidification of the Environment in Saccharomyces cerevisiae
por: Maruyama, Yo, et al.
Publicado: (2016)

Myc-Dependent Genome Instability and Lifespan in Drosophila
por: Greer, Christina, et al.
Publicado: (2013)

Acetic acid and acidification accelerate chronological and replicative aging in yeast
por: Mirisola, Mario G., et al.
Publicado: (2012)

The Anti-Aging Potential of Neohesperidin and Its Synergistic Effects with Other Citrus Flavonoids in Extending Chronological Lifespan of Saccharomyces Cerevisiae BY4742
por: Guo, Chunxia, et al.
Publicado: (2019)

Maintenance of Mitochondrial Morphology by Autophagy and Its Role in High Glucose Effects on Chronological Lifespan of Saccharomyces cerevisiae
por: Aung-Htut, May T., et al.
Publicado: (2013)

Low doses of DNA damaging agents extend Saccharomyces cerevisiae chronological lifespan by promoting entry into quiescence
por: Ross, Emily M., et al.
Publicado: (2018)

Extension of Yeast Chronological Lifespan by Methylamine
por: Kumar, Sanjeev, et al.
Publicado: (2012)

Extension of chronological lifespan in Schizosaccharomyces pombe
por: Ohtsuka, Hokuto, et al.
Publicado: (2021)

Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast
por: Liu, Jun, et al.
Publicado: (2016)

Genome-wide screens in yeast models towards understanding chronological lifespan regulation
por: Legon, Luc, et al.
Publicado: (2021)

The significance of peroxisome function in chronological aging of Saccharomyces cerevisiae
por: Lefevre, Sophie D, et al.
Publicado: (2013)

Mitochondrial Aminopeptidase Deletion Increases Chronological Lifespan and Oxidative Stress Resistance while Decreasing Respiratory Metabolism in S. cerevisiae
por: Stames, Erine M., et al.
Publicado: (2013)

Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system
por: Madia, Federica, et al.
Publicado: (2008)

Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polζ-dependent mechanism
por: Madia, Federica, et al.
Publicado: (2009)

Cell-autonomous mechanisms of chronological aging in the yeast Saccharomyces cerevisiae
por: Arlia-Ciommo, Anthony, et al.
Publicado: (2014)

Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast
por: Stępień, Karolina, et al.
Publicado: (2019)

Rec-8 dimorphism affects longevity, stress resistance and X-chromosome nondisjunction in C. elegans, and replicative lifespan in S. cerevisiae
por: Ayyadevara, Srinivas, et al.
Publicado: (2014)

Ammonium Is Toxic for Aging Yeast Cells, Inducing Death and Shortening of the Chronological Lifespan
por: Santos, Júlia, et al.
Publicado: (2012)

Chronological and replicative lifespan in yeast: Do they meet in the middle?
por: Polymenis, Michael, et al.
Publicado: (2012)

Pathologic Replication-Independent Endogenous DNA Double-Strand Breaks Repair Defect in Chronological Aging Yeast
por: Pongpanich, Monnat, et al.
Publicado: (2018)

Distinct structural groups of histone H3 and H4 residues have divergent effects on chronological lifespan in Saccharomyces cerevisiae
por: Ngubo, Mzwanele, et al.
Publicado: (2022)

CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging
por: Peclat, Thais R., et al.
Publicado: (2022)

The Use of Murine Models for Studying Mechanistic Insights of Genomic Instability in Multiple Myeloma
por: Vlummens, Philip, et al.
Publicado: (2019)

Natural variation of chronological aging in the Saccharomyces cerevisiae species reveals diet-dependent mechanisms of life span control
por: Jung, Paul P., et al.
Publicado: (2018)

In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase
por: Baroni, Maurizio D., et al.
Publicado: (2020)

Chronological lifespan in stationary culture: from yeast to human cells
por: Demidenko, Zoya N.
Publicado: (2011)

Coffee Extends Yeast Chronological Lifespan through Antioxidant Properties
por: Czachor, Jadwiga, et al.
Publicado: (2020)

How does genome instability affect lifespan?
por: Kobayashi, Takehiko
Publicado: (2011)

Regulation of lifespan by chemosensory and thermosensory systems: findings in invertebrates and their implications in mammalian aging
por: Jeong, Dae-Eun, et al.
Publicado: (2012)

Different Expression Levels of Human Mutant Ubiquitin B(+1) (UBB(+1)) Can Modify Chronological Lifespan or Stress Resistance of Saccharomyces cerevisiae
por: Muñoz-Arellano, Ana Joyce, et al.
Publicado: (2018)

Epigenetics across the human lifespan
por: Kanherkar, Riya R., et al.
Publicado: (2014)

A Network-Based Approach on Elucidating the Multi-Faceted Nature of Chronological Aging in S. cerevisiae
por: Borklu Yucel, Esra, et al.
Publicado: (2011)

Communications between Mitochondria, the Nucleus, Vacuoles, Peroxisomes, the Endoplasmic Reticulum, the Plasma Membrane, Lipid Droplets, and the Cytosol during Yeast Chronological Aging
por: Dakik, Pamela, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_q5rltal09rbj87ohn8vttug8gh