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In silico discovery of novel Retinoic Acid Receptor agonist structures
BACKGROUND: Several Retinoic Acid Receptors (RAR) agonists have therapeutic activity against a variety of cancer types; however, unacceptable toxicity profiles have hindered the development of drugs. RAR agonists presenting novel structural and chemical features could therefore open new avenues for...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC32304/ https://www.ncbi.nlm.nih.gov/pubmed/11405897 http://dx.doi.org/10.1186/1472-6807-1-1 |