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Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture
Background: Pyrethroid insecticides bind to voltage-gated sodium channels and modify their gating kinetics, thereby disrupting neuronal function. Although previous work has tested the additivity of pyrethroids in vivo, this has not been assessed directly at the primary molecular target using a funct...
Autores principales: | Cao, Zhengyu, Shafer, Timothy J., Crofton, Kevin M., Gennings, Chris, Murray, Thomas F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230403/ https://www.ncbi.nlm.nih.gov/pubmed/21665567 http://dx.doi.org/10.1289/ehp.1003394 |
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