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Oral fondaparinux: use of lipid nanocapsules as nanocarriers and in vivo pharmacokinetic study
Oral anticoagulant therapy could be advanced using lipid-based nanoparticulate systems. This study examined lipid nanocapsules for their oral absorption potential as the first step in developing oral fondaparinux (Fp) novel carriers. Using phase inversion method and cationic surfactants such as hexa...
Autores principales: | Ramadan, Alyaa, Lagarce, Frederic, Tessier-Marteau, Anne, Thomas, Olivier, Legras, Pierre, Macchi, Laurent, Saulnier, Patrick, Benoit, Jean Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230563/ https://www.ncbi.nlm.nih.gov/pubmed/22162653 http://dx.doi.org/10.2147/IJN.S25791 |
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