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The human sirtuin family: Evolutionary divergences and functions
The sirtuin family of proteins is categorised as class III histone deacetylases that play complex and important roles in ageing-related pathological conditions such as cancer and the deregulation of metabolism. There are seven members in humans, divided into four classes, and evolutionarily conserve...
Autores principales: | Vassilopoulos, Athanassios, Fritz, Kristofer S, Petersen, Dennis R, Gius, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230576/ https://www.ncbi.nlm.nih.gov/pubmed/21807603 http://dx.doi.org/10.1186/1479-7364-5-5-485 |
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