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Antiviral Activity of Bay 41-4109 on Hepatitis B Virus in Humanized Alb-uPA/SCID Mice
Current treatments for HBV chronic carriers using interferon alpha or nucleoside analogues are not effective in all patients and may induce the emergence of HBV resistant strains. Bay 41-4109, a member of the heteroaryldihydropyrimidine family, inhibits HBV replication by destabilizing capsid assemb...
Autores principales: | Brezillon, Nicolas, Brunelle, Marie-Noëlle, Massinet, Hélène, Giang, Eric, Lamant, Céline, DaSilva, Lucie, Berissi, Sophie, Belghiti, Jacques, Hannoun, Laurent, Puerstinger, Gherard, Wimmer, Eva, Neyts, Johan, Hantz, Olivier, Soussan, Patrick, Morosan, Serban, Kremsdorf, Dina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230577/ https://www.ncbi.nlm.nih.gov/pubmed/22162746 http://dx.doi.org/10.1371/journal.pone.0025096 |
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