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Structure of the Bro1 Domain Protein BROX and Functional Analyses of the ALIX Bro1 Domain in HIV-1 Budding

BACKGROUND: Bro1 domains are elongated, banana-shaped domains that were first identified in the yeast ESCRT pathway protein, Bro1p. Humans express three Bro1 domain-containing proteins: ALIX, BROX, and HD-PTP, which function in association with the ESCRT pathway to help mediate intraluminal vesicle...

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Detalles Bibliográficos
Autores principales: Zhai, Qianting, Landesman, Michael B., Robinson, Howard, Sundquist, Wesley I., Hill, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230590/
https://www.ncbi.nlm.nih.gov/pubmed/22162750
http://dx.doi.org/10.1371/journal.pone.0027466

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