The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis

Telomerase is a ribonucleoprotein (RNP) enzyme that maintains the ends of linear eukaryotic chromosomes and whose activation is a hallmark of 90% of all cancers. This RNP minimally contains a reverse transcriptase protein subunit (TERT) that catalyzes telomeric DNA synthesis and an RNA subunit (TER)...

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Detalles Bibliográficos
Autores principales: Berman, Andrea J., Akiyama, Benjamin M., Stone, Michael D., Cech, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230705/
https://www.ncbi.nlm.nih.gov/pubmed/22101935
http://dx.doi.org/10.1038/nsmb.2174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230705/
https://www.ncbi.nlm.nih.gov/pubmed/22101935
http://dx.doi.org/10.1038/nsmb.2174

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