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The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS
RNA interference (RNAi) is critical for the assembly of heterochromatin at fission yeast centromeres. Central to this process is the RNA-induced Initiation of Transcriptional gene Silencing (RITS) complex, which physically anchors small non-coding RNAs to chromatin. RITS includes Ago1, the chromodom...
Autores principales: | Schalch, Thomas, Job, Godwin, Shanker, Sreenath, Partridge, Janet F., Joshua-Tor, Leemor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230742/ https://www.ncbi.nlm.nih.gov/pubmed/22081013 http://dx.doi.org/10.1038/nsmb.2151 |
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