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Mice Lacking Ras-GRF1 Show Contextual Fear Conditioning but not Spatial Memory Impairments: Convergent Evidence from Two Independently Generated Mouse Mutant Lines
Ras-GRF1 is a neuronal specific guanine exchange factor that, once activated by both ionotropic and metabotropic neurotransmitter receptors, can stimulate Ras proteins, leading to long-term phosphorylation of downstream signaling. The two available reports on the behavior of two independently genera...
Autores principales: | d’Isa, Raffaele, Clapcote, Steven J., Voikar, Vootele, Wolfer, David P., Giese, Karl Peter, Brambilla, Riccardo, Fasano, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230787/ https://www.ncbi.nlm.nih.gov/pubmed/22164138 http://dx.doi.org/10.3389/fnbeh.2011.00078 |
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